TLC-based fingerprinting for Phyllanthus niruri from diverse geographical origins in East and Central Java Indonesia

نویسندگان

چکیده

Abstract Phyllanthus niruri L. (meniran), the member of Euphorbiaceae , is a medicinal plant that commonly found in tropical and sub-tropical areas such as Asia, America, China. Various factors environment, geographical location, harvest time, post-harvest process can affect quality crude drugs produced from P. . The objective this study was to evaluate meniran herbs obtained 15 origins East Central Java, Indonesia using Thin Layer Chromatography (TLC) profiles analyzed by chemometrics. TLC carried out plate Si Gel 60 GF254 stationary phase; toluene, ethyl acetate, methanol, 85% formic acid (75:25:25:6) mobile visualized NP/PEG Reagent. results showed TLC-fingerprinting combined with chemometric (PCA CA) analyses were able discriminate origin different origins. locations Java classified into 5 groups based on their chemical similarity. samples are grouped one cluster have similar compounds, while clusters also qualities.

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ژورنال

عنوان ژورنال: IOP conference series

سال: 2021

ISSN: ['1757-899X', '1757-8981']

DOI: https://doi.org/10.1088/1755-1315/948/1/012003